Some Interesting Facts About Telomeres
These days, there are various reasons why testing using telomerase analysis technology (TAT) is becoming popular. Essentially, this test serves as a biomarker to determine the early prognosis and risk of certain diseases like cancer. The process involves a comprehensive analysis and evaluation of the length of the telomere. There is a link between the length of telomeres and various age-related diseases. Telomeres may be used as an individual biomarker or in combination with other biomarkers. Telomeres are very convenient biomarkers because you can get them from various body samples. Understanding telomeres helps a lot for those who are planning to make use of telomerase analysis technology. This article will provide you with some interesting facts about telomeres now.
Age-related disorders are associated with the length of your telomeres as mentioned earlier. Getting older is a normal part of life. To this day, many scientists are still puzzled over why people age and what causes aging. Many theories are published year after year, such DNA being affected and damaged by oxidative stress. Should glucose be blamed as well? Perhaps the human body have cells that follow a well-programmed biological timetable? For sure, aging is caused by a combination of all these factors and many more.
One of the most highly supported theories of aging will have to be one that links the natural process to telomeres. Telomeres are essentially found in your DNA molecules at their end as tiny protective caps, which make up all of your chromosomes. Their main role is to ensure that the ends of your chromosomes don’t end up sticking to each other or fraying.
When cells go through division, telomeres make sure that the person’s DNA will be copied properly. Unfortunately, there are some instances in DNA replication that some of the building blocks of DNA or nucleotides found at the end of the strand are unable to make it into the new copy of the DNA. The outcome will be a loss of some crucial genetic information. DNA strands naturally shorter with every division of the cells.
Now, why do cells still get some DNA left after all the division that they go through? This part is where telomeres play a significant role. Telomeres comprise the same DNA sequence repeated time and time again, making them somehow disposable. They make sure to keep the rest of the DNA protected. Even if they get shorter time and time again, they will make sure not to lose your genetic information.
With the role of telomeres, when they shorten, they can be a factor that associates with the aging of cells. Cells cannot divide like they should when they have too short telomeres. If they reach a crucial point, the cell now becomes inactive that either make them accumulate damage they can’t fix or they simply die.